Pan African Journal of Life Sciences(PAJOLS)

A publication of Faculty of Basic Medical Sciences, Ladoke Akintola University of Technology, Ogbomoso

PAN AFRICAN JOURNAL OF LIFE SCIENCES
e-ISSN: 2672-5924
Volume 3, No. 1,  2019
Pages 157-182

DOI: 10.36108/pajols/9102/30(0170)

Biomedical Applications of Green Synthesized-Metallic Nanoparticles: A Review
Agbaje Lateef1,2, Joseph A. Elegbede1, Paul O. Akinola1, Victoria A. Ajayi3
1Laboratory of Industrial Microbiology and Nanobiotechnology, Department of Pure and Applied Biology
2Nanotechnology Research Group (NANO+)
3Department of Science Laboratory Technology, Ladoke Akintola Univer-sity of Technology, PMB 4000, Ogbomoso, Nigeria

Abstract

Advances in the field of nanoscience and nanotechnology to modulate materials at nanoscale level has continued to have great impact on different disciplines of science and engineering as well as agriculture and medical fields. The surge in the utilization of benign and non-toxic biomolecules to engineer enhanced biocompatible nanomaterials has contributed to a large extent to the applications of nanomaterials in healthcare; an emerging sub-discipline termed nanomedicine. Among the several nanomaterials that have been produced, metallic nanoparticles occupy prime position owing to their optical, catalytic and biological characteristics. These nanoparticles, which are of different types existing singly as mono-metallic nanoparticles or in two or more metals as alloys have found extremely useful applications as antimicrobial, antioxidant, anticancer, antidiabetic, anticoagulant and thrombolytic agents amongst others. In this review, an attempt is made to project the different applications of green synthesized metallic nanoparticles in diverse areas of biomedicine, including the discussion of issues of toxicity and prospects of nanotechnology in biomedical field.
Keywords: Biomedicine, green synthesis, nanoparticles, nanomedicine, nanoscience, nanotechnology

 

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