PAN AFRICAN JOURNAL OF LIFE SCIENCES
e-ISSN: 2672-5924
Volume 7, No. 2, August 2023
Pages 676-681
DOI: 10.36108/pajols/3202/70.0270
Interplay between Lipid Profile and Weight-Related Outcomes in Healthy Overweight Adults: In-sights from Comprehensive Analyses
Louis O. Odeigah1, Olalekan A. Agede2*, Sunday B. Ogunjemilua3, Ismaila A. Obalowu4, Yahkub B. Mutalub5
1Department of Family Medicine, University of Ilorin and University of Ilorin Teaching Hospital, Ilorin, Nigeria
2Department of Medicine and Pharmacology, Division of Clinical Pharmacology and Therapeutics, University of Ilorin and University of Ilorin Teaching Hospital, Ilorin, Nigeria
3Department of Family Medicine, University of Ilorin Teaching Hospital, Ilorin, Nigeria
4Department of Family Medicine, General Hospital, Ilorin, Nigeria
5Department of Clinical Pharmacology, College of Medical Sciences, Abubakar Tafawa Balewa University, Bauchi, Nigeria
Abstract
Background: The escalating prevalence of overweight and obesity has heightened concerns about cardiovascular health. The intricate interplay between lipid profile variables and weight-related outcomes plays a pivotal role in shaping cardiovascular risks among individuals with excess body weight. This study investigates the associations between lipid profile variables and weight-related indicators in a cohort of healthy, overweight adults, shedding light on potential implications for cardiovascular risk management.
Methods: The prevalence of metabolic syndrome, risk factors, and related lifestyle in adult Myanmar citizens were examined in the Inter-University Consortium for Political and Social Research Study (ICPSR146521) using prospective data. The patient’s lipid profiles and demographic data were statistically analyzed using the statistical MedCalc tool. Statistical significance was determined using a 0.05 p-value.
Results: Results demonstrate that while BMI is influenced by multiple factors beyond lipid profile variables, waist circumference exhibits moderate association with these variables. Notably, triglycerides significantly correlated with waist circumference, suggesting a potential role in visceral fat accumulation. Additionally, the study highlights the impact of high-density lipoprotein (HDL) cholesterol levels on body weight, indicating that higher HDL levels are associated with lower body weights among healthy overweight adults.
Conclusion: This study provides comprehensive insights into the complex relationship between lipid profile variables and weight-related outcomes among healthy, overweight adults. These findings underscore the importance of weight management strategies for cardiovascular health and suggest potential avenues for targeted interventions. By understanding the interplay between lipid profiles and obesity, clinicians and public health professionals can develop more effective strategies to mitigate cardiovascular risks in this demographic
Keywords: BMI, HDL, LDL, overweight, dyslipidemia, waist circumference